Bispecifc antibodies (bsAb) are molecules that can steer immune cells, such as T cells, NK cells, towards cancer cells. They facilitate the formation of the immunological synapses (IS), which are key driver of downstream T cell response. In this webinar, our principal scientist will show how cell avidity measures the effectiveness of the events during IS formation, and allow researchers to rank and select the best candidates.
Learning objectives:
– Whether exploring TCR or CAR-T or other cell-cell binding including that induced by cell engagers, cell avidity analysis is a fast and simple method to rank and select best candidates.
– Increasing bsAb avidity has been shown to correlate with improved functionality.
– The z-Movi® Cell Avidity Analyzer is a novel and unique instrument for direct measurement of cell–cell interaction strength using acoustic forces, providing predictive, reproducible and fast results at a single-cell level.
